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Data Access Register - full project summary

Application ID llc_0005
Project Title Are immune-mediated diseases risk factors for long COVID?
Lead Applicant Dylan Williams
Organisation(s) Name(s) University College London (UCL)
Approval Date 2021-10-28
Application Status Approved
Lay Summary

Inflammation is the process of the body fighting against infection and injury. In inflammatory disorders and allergies this reaction is worse and harms the healthy body. In this study we hope to find out whether people with chronic inflammatory disorders and allergies are more likely to have long-lasting symptoms after Covid infection (long COVID). The findings will let us know whether:

  • inflammation plays a role in long Covid
  • people within flammatory disorders and allergies should receive a booster vaccine
  • existing medications for inflammatory disorders and allergies could be used to treat or prevent long Covid
Datasets Requested
  • National Survey of Health and Development (NSHD, 1946 British Birth Cohort Study
  • Southall and Brent Revisited Study (SABRE) (non-linked data only)
  • English Longitudinal Study of Ageing (ELSA)
  • 1958 National Child Development Study (1958 NCDS)
  • British Cohort Study 1070 (BCS 70)
  • Next Steps
  • Millennium Cohort Study (MCS)
  • Genetic Links to Anxiety and Depression (GLAD) Study
  • Twins UK
  • Track-COVID
  • NIHR BioResource
  • Extended Cohort for E-Health, Environment & DNA (EXCEED)
  • Understanding Society
  • Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA)
  • Born in Bradford
  • Generation Scotland

NHS Digital Covid-19 Datasets (linked datasets for participants in linked studies):

  • Covid 19 Vaccination Status
  • GPES Data for Pandemic Planning and Research (COVID-19)
  • Covid-19 UK Non-Hospital Antigen Testing Results (Pillar 2)
  • Medicines Dispensed in Primary Care (NHSBSA Data)
  • Hospital Episode Statistics Critical Care
  • Hospital Episode Statistics Admitted Patient Care
  • Hospital Episode Statistics Outpatient
  • Hospital Episode Statistics Accident and Emergency
  • COVID-19 SARI-WATCH (formerly CHESS)
  • Covid-19 Second Generation Surveillance System (Pillar 1)
  • Covid-19 UK Non-hospital Antibody Testing Results (Pillar 3)
  • Civil Registration – Deaths
  • ECOSS (COVID Testing)
  • NHS Prescription Data (PIS)
  • SMR01 General / Acute Inpatient and Day Case
  • NHS Vaccination Data
Results & Impact